Winston-Salem to Knoxville: where to stop

A stop about every 45 minutes

The best bet in each stretch: a likely-clean restroom first, then a travel center or gas. Estimates come from who runs the store until drivers review it.

• 152 Wytheville · Charlotte Likely cleanest. Cracker Barrel Old Country Store Statesville · 41 mi from Winston-Salem 45 min in
• 103 Morganton · Rutherfordton Likely cleanest. Chick-fil-A Morganton · 91 mi from Winston-Salem 1 hr 30 min in
• 44 West Asheville · Enka · Candler Likely cleanest. Cracker Barrel 150 mi from Winston-Salem 2 hr 15 min in
• 435 Newport · Gatlinburg Likely cleanest. Cracker Barrel Newport · 210 mi from Winston-Salem 3 hr 15 min in

Long stretches without a likely-clean stop

• 60 miles, about 1 hr: from Exit 44 (NC) to Exit 435 (TN). Stop before it if you can.

Other drives on I-40

• Raleigh to Knoxville
• Winston-Salem to Asheville
• Winston-Salem to Cookeville
• Asheville to Knoxville
• Memphis to Knoxville
• Jackson to Knoxville
• Nashville to Knoxville
• Cookeville to Knoxville