Knoxville to Winston-Salem: where to stop

A stop about every 45 minutes

The best bet in each stretch: a likely-clean restroom first, then a travel center or gas. Estimates come from who runs the store until drivers review it.

• 435 Newport · Gatlinburg Likely cleanest. Cracker Barrel Newport · 47 mi from Knoxville 45 min in
• 44 West Asheville · Enka · Candler Likely cleanest. Cracker Barrel 108 mi from Knoxville 1 hr 45 min in
• 103 Morganton · Rutherfordton Likely cleanest. Chick-fil-A Morganton · 166 mi from Knoxville 2 hr 30 min in
• 125 Hickory · Lenoir-Rhyne College Likely cleanest. Cracker Barrel Old Country Store Hickory · 188 mi from Knoxville 3 hr in

Long stretches without a likely-clean stop

• 61 miles, about 1 hr: from Exit 435 (TN) to Exit 44 (NC). Stop before it if you can.

Other drives on I-40

• Raleigh to Winston-Salem
• Knoxville to Cookeville
• Knoxville to Nashville
• Knoxville to Jackson
• Knoxville to Memphis
• Cookeville to Winston-Salem
• Knoxville to Asheville
• Knoxville to Raleigh