Harrisburg to Syracuse: where to stop

A stop about every 45 minutes

The best bet in each stretch: a likely-clean restroom first, then a travel center or gas. Estimates come from who runs the store until drivers review it.

• 124A St Clair Likely cleanest. Cracker Barrel Old Country Store Frackville · 57 mi from Harrisburg 1 hr in
• 168 Wilkes-Barre · Highland Park Boulevard Likely cleanest. Chick-fil-A Wilkes-Barre · 102 mi from Harrisburg 1 hr 30 min in
• 219 Gibson Mixedest. Flying J 153 mi from Harrisburg 2 hr 15 min in
• 15 Exit 15 Likely cleanest. Cracker Barrel Port Dickinson · 181 mi from Harrisburg 2 hr 45 min in

Long stretches without a likely-clean stop

• 78 miles, about 1 hr 15 min: from Exit 168 (PA) to Exit 13B (NY). Stop before it if you can.
• 71 miles, about 1 hr: from Exit 15 (NY) to Syracuse. Stop before it if you can.

Other drives on I-81

• Harrisburg to Winchester
• Harrisburg to Harrisonburg
• Winchester to Syracuse
• Harrisburg to Scranton
• Harrisburg to Binghamton
• Harrisburg to Watertown
• Scranton to Syracuse