Columbia to Indianapolis: where to stop

A stop about every 45 minutes

The best bet in each stretch: a likely-clean restroom first, then a travel center or gas. Estimates come from who runs the store until drivers review it.

• 175 Hermann · New Florence Mixedest. Love's New Florence · 49 mi from Columbia 45 min in
• 225 Cave Springs Road · Truman Road Likely cleanest. QuikTrip Saint Peters · 99 mi from Columbia 1 hr 30 min in
• 20A Exit 20A Likely cleanest. Cracker Barrel Troy · 142 mi from Columbia 2 hr 15 min in
• 162 Sigel · Effingham Likely cleanest. QuikTrip Effingham · 225 mi from Columbia 3 hr 30 min in
• 119 Haughton Highway Mixedest. Love's Greenup · 247 mi from Columbia 3 hr 45 min in
• 11A-B US-40 East · SR 641 South · SR 46 Mixedest. ONE9 294 mi from Columbia 4 hr 30 min in

Long stretches without a likely-clean stop

• 79 miles, about 1 hr 15 min: from Exit 128A (MO) to Exit 208 (MO). Stop before it if you can.
• 82 miles, about 1 hr 15 min: from Exit 20A (IL) to Exit 162 (IL). Stop before it if you can.
• 125 miles, about 2 hr: from Exit 162 (IL) to Exit 66 (IN). Stop before it if you can.

Other drives on I-70

• Columbia to Kansas City
• Columbia to Topeka
• Columbia to Salina
• Columbia to Hays
• Columbia to St. Louis
• Columbia to Effingham
• Columbia to Terre Haute
• St. Louis to Indianapolis