Memphis to St. Louis: where to stop

A stop about every 45 minutes

The best bet in each stretch: a likely-clean restroom first, then a travel center or gas. Estimates come from who runs the store until drivers review it.

• 48 Osceola Mixedest. 51 mi from Memphis 45 min in
• 19 Hayti · Caruthersville Mixedest. Exxon Hayti · 94 mi from Memphis 1 hr 30 min in
• 96 Cape Girardeau · Gordonville Likely cleanest. Cracker Barrel Cape Girardeau · 172 mi from Memphis 2 hr 45 min in
• 129 Perryville Mixedest. Burger King Perryville · 205 mi from Memphis 3 hr 15 min in
• 178 Herculaneum · McNutt Street Likely cleanest. QuikTrip Festus · 254 mi from Memphis 4 hr in

Long stretches without a likely-clean stop

• 162 miles, about 2 hr 30 min: from Exit 277 (AR) to Exit 96 (MO). Stop before it if you can.
• 82 miles, about 1 hr 15 min: from Exit 96 (MO) to Exit 178 (MO). Stop before it if you can.

Other drives on I-55

• Chicago to St. Louis
• Bloomington-Normal to St. Louis
• Springfield to St. Louis
• Memphis to Cape Girardeau
• Memphis to Springfield
• Cape Girardeau to St. Louis